SeriesLock™ NPT 100 Quick Disconnect Couplings and Inserts

A unique aseptic Spring-Free Flow Path® quick-connect fitting allows a larger volume of fluid to pass through it at lower line pressures. This optimized flow reduces restriction, turbidity, foaming, and bubbles. Recessed mating features protect contact surfaces and prolong the life of the O-rings helping to ensure a better seal. The audible click upon connection and the safety slide release are both features to help minimize accidental disconnects. Three body sizes in Small, Medium, and Large are available to accommodate a variety of connection sizes for NPT thread adapters. Additional sizes, materials, flow paths, and end connections available; contact us for a quote.

  • Natural Kynar® (PVDF), Glass Filled Black Nylon (GFBN), Polypropylene (PP), or Polysulfone (PS)
  • PP, PS & PVDF have silicone O-ring & GFBN has Viton™; 302 stainless steel spring
  • Spring-Free Flow Path® fittings – valved; Superior single barb technology
  • Lubricant: biocompatible & inert PFPE
  • Slide button & main latch: CrystalVu™ PMP copolymer
  • Spillage < 0.05cc per disconnect (small & medium) & < 0.1cc per disconnect (large)
  • Sterilization: EtO, Gamma & E-Beam, Autoclavable
  • Working pressure: vacuum to 90 psi, 6.9 bar
  • Temp. range: GFBN (32°F to 450°F), PP (32°F to 160°F), PVDF (32°F to 250°F), PS (-40°F to 282°F)
  • USP Class VI & ISO10993 Compliant (PVDF & Polypropylene)
Stock Description Catalog Pg. Price Add to Cart
1/8" NPT x 1/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Small
Item 63375
21.06/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
21.06/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Small
Item 63376
21.06/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
21.06/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63377
22.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.12/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63378
22.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.12/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63379
22.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.12/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Medium
Item 63380
22.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.12/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Large
Item 63381
27.06/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
27.06/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Kynar® Female SeriesLock™ Valved Coupling - Large
Item 63382
27.06/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
27.06/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Small
Item 63383
13.89/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.89/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Small
Item 63384
12.82/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.82/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63385
14.28/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
14.28/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63386
13.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.21/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63387
13.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.21/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Medium
Item 63388
14.28/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
14.28/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Large
Item 63389
18.02/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.02/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Kynar® Male SeriesLock™ Valved Insert - Large
Item 63390
16.96/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.96/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Small
Item 63359
17.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.21/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Small
Item 63360
17.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.21/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63361
17.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.36/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63362
17.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.36/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63363
17.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.36/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Medium
Item 63364
17.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.36/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Large
Item 63365
18.84/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.84/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polypropylene Female SeriesLock™ Valved Coupling - Large
Item 63366
18.84/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.84/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Small
Item 63367
12.15/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.15/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Small
Item 63368
11.08/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
11.08/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63369
12.25/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.25/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63370
11.19/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
11.19/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63371
11.19/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
11.19/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Medium
Item 63372
12.25/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.25/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Large
Item 63373
13.86/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.86/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polypropylene Male SeriesLock™ Valved Insert - Large
Item 63374
12.78/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.78/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Small
Item 63391
21.91/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
21.91/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Small
Item 63392
21.91/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
21.91/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63393
22.84/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.84/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63394
22.91/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.91/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63395
22.84/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.84/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Medium
Item 63396
22.87/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
22.87/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Large
Item 63397
27.69/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
27.69/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polysulfone Female SeriesLock™ Valved Coupling - Large
Item 63398
28/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
28/Each
1/8" NPT x 1/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Small
Item 63399
13.95/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.95/Each
1/8" NPT x 3/16" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Small
Item 63400
12.89/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.89/Each
1/4" NPT x 1/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63401
15.13/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
15.13/Each
1/4" NPT x 3/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63402
14.15/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
14.15/Each
3/8" NPT x 1/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63403
14.06/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
14.06/Each
3/8" NPT x 3/8" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Medium
Item 63404
15.21/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
15.21/Each
1/2" NPT x 1/2" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Large
Item 63405
18.58/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.58/Each
1/2" NPT x 3/4" Tubing Equivalent Natural Polysulfone Male SeriesLock™ Valved Insert - Large
Item 63406
17.89/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
17.89/Each
1/8" NPT x 1/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Small
Item 63407
16.5/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.5/Each
1/8" NPT x 3/16" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Small
Item 63408
16.5/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.5/Each
1/4" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63409
16.97/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.97/Each
1/4" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63410
16.99/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.99/Each
3/8" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63411
16.97/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.97/Each
3/8" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Medium
Item 63412
16.99/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
16.99/Each
1/2" NPT x 1/2" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Large
Item 63413
18.67/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.67/Each
1/2" NPT x 3/4" Tubing Equivalent Glass Filled Black Nylon Female SeriesLock™ Valved Coupling - Large
Item 63414
18.8/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
18.8/Each
1/8" NPT x 1/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Small
Item 63415
13.27/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.27/Each
1/8" NPT x 3/16" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Small
Item 63416
10.12/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
10.12/Each
1/4" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63417
11.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
11.36/Each
1/4" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63418
10.29/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
10.29/Each
3/8" NPT x 1/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63419
10.29/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
10.29/Each
3/8" NPT x 3/8" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Medium
Item 63420
11.36/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
11.36/Each
1/2" NPT x 1/2" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Large
Item 63421
13.1/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
13.1/Each
1/2" NPT x 3/4" Tubing Equivalent Glass Filled Black Nylon Male SeriesLock™ Valved Insert - Large
Item 63422
12.1/Each
Save 5% when you buy 5+
Save 10% when you buy 10+
Save 15% when you buy 30+
P-253
12.1/Each